The Sclerotinia sclerotiorum Bary fungi causes collar rot in the tobacco seedlings in the seedbed. The purpose of this project was to carry out a performance survey of the fungicides Vista (active ingredient Tricyclazole 37.5 % + Thiophanate methyl 35 %, WP 72.5 %), Nativo (active ingredient Tebuconazole 50 % + Trifloxystrobin 25 %, WG 75 %) and Topsin M (active ingredient Thiophanate methyl WP 70 %) for tobacco collar rot disease management. The experiments were carried out in a completely randomized design with fungicides of Vista, Nativo and Topsin M at concentrations of 0, 50, 100, 150, 200 and 250 ppm with 16 treatments in four replications. Another experiment under float seedbed conditions was carried out on the K326 variety with fungicides Vista at concentrations of 400, 500 and 600 g/ha (1, 1.25 and 1.5/1000), Nativo at concentrations of 120, 160 and 200 g/ha (0.3, 0.4 and 0.5/1000), and Topsin M at concentrations of 800 g/ha (2/1000) and control (check) treatment spray with water with eight treatments and three in replications in a randomized complete block design at the Tirtash Research and Education Center in Northern Iran in 2019. Design data was analyzed with MSTAT-C software and mean comparison was done by LSD. The results of variance analysis showed there was a significant difference among the treatments at the 1 % probability level. At the laboratory, all treatments, except for Vista treatment, 50 ppm (93 %) and control (0 %) prevented 100 % mycelium growth of sclerotinia fungi. In the seedbed, the Topsin M fungicides with a concentration of 800 g/ha (2/1000), Nativo at concentrations of 200, 160 and 120 g/ha (0.5, 0.4 and 0.3 /1000), and Vista with concentrations of 600, 500 and 400 g/ha (1.5, 25.1 and 1/1000), respectively, showed 100 %, 100 %, 100 %, 96 %, 96 %, 93 % and 88 % control of tobacco collar rot disease. Therefore, fungicides of Vista with a concentration of 400 g/ha (1/1000) and Nativo with a concentration of 120 g/ha (0.3/1000) are recommended for the management of tobacco collar rot disease in the seedbed.