Skip to main content
CORESTA Meeting, Smoke Science/Product Technology, 2023, Cancun, STPOST 32

Simultaneous determination of six furans in aerosol of heated tobacco products by gas chromatography/mass spectrometry

ZHANG Li(1); WANG Weiwei(1); WANG Bing(2); DONG Rui(1); YIN Fang(1); TONG Fuqiang(1); JI Houwei(1); LIU Yuming(1)
(1) Technology Center, China Tobacco Guizhou Industrial Co., Ltd., Guiyang, China; (2) Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, China

Due to the absence of high-temperature pyrolysis and combustion, the releases of most harmful components from heated tobacco products (HTPs) are much lower than those from conventional cigarettes (CCs). However, some harmful components were reported to be released at higher levels than CCs, including furans. Furans, which are harmful or potentially harmful to humans, are an important class of baked aroma components in cigarette smoke. To investigate the release characteristics of furans in the aerosol of HTPs, a gas chromatography/mass spectrometry (GC/MS) method was established. The releases and distributions of six furans in the aerosols of eight HTPs and three CCs were investigated under ISO and HCI regimes. The effects of different heating temperatures on the release efficiencies of six furans were also investigated. The results showed that: 1) The calibration curves showed good linearity for six furans and the correlation coefficients (r2) were 0.9989-0.9999. The limits of detection (LODs) and limits of quantification (LOQs) were 0.01-0.12 µg/cig and 0.02-0.39 µg/cig, respectively. Recoveries were in the range of 95.33 % to 108.66 % and the relative standard deviations (RSDs) were 1.33 % to 8.51 %. 2) Furfural, 5-methylfurfural, 2-acetylfuran and furanmethanol were distributed in the gas phase and particle phase, and the proportions in the gas phase under HCI regime were higher than those under ISO regime; while 5-methyl-2-furanmethanol, and 5-hydroxymethylfurfural were mainly distributed in the particle phase. 3) The main furans in the aerosol of HTPs were furanmethanol and furfural, and the release amounts of furanmethanol, furfural, and 5-methylfurfural in the aerosol of some HTPs were higher than those of CCs with ratios ranging from 1.73 to 5.65. 4) Under low-temperature heating conditions, the release amounts of six furans in the aerosol of HTPs increased with increasing heating temperature. The proposed method is simple, sensitive and suitable for the determination of six furans in the aerosol of HTPs, and provides technical support for the product design and quality control of HTPs.