Bull. ARN, 2006, p. 56-73., ISSN.1146-6200.
Association of lung function decline with the microsatellite polymorphism in the heme oxygenase-1 gene promoter, in a general population sample. Results from the European Community Respiratory Health Survey (ECRHS), France
INSERM U700 Epidemiologie, Fac. de Médecine Xavier Bichat, Paris, France
Heme oxygenase (HO-1) acts against oxidants which are thought to play a major role in the pathogenesis of chronic obstructive pulmonary disease (COPD), characterised by impaired lung function. A (GT)n repeat polymorphism in the HO-1 gene promoter can...