CORESTA Meeting, Smoke Science/Product Technology, Stratford-upon-Avon, 2005, SSPT 30
Determination of NNAL in smokers' urine by LC-MS/MS: a comparison of sample preparation procedures
British American Tobacco Italia, R&D, Naples, Italy
4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) is a potent pulmonary carcinogen in rodents and may play a significant role as a cause of lung cancer in smokers. NNK uptake can be quantified by the analysis of two of its metabolites in urine,...