It has already been clearly shown in many studies that tobacco absorbs with relative ease cadmium, but the translocation to its leaves differs with species. For this reason, different trials have been carried out in pots to define the comportment of N. tabacum, variety PB D6. The influence of the cadmium concentration of the growth medium and the form of nitrogen on cadmium content have been studied in hydroponic culture. In soil culture, the influence of pH modified by increasing amounts ofCaCO3 (from 0,5 to 15% of the earth's weight) and those of nitrate compared to ammoniac have been precisely defined. The studies confirm that N. tabacum may easily absorb cadmium without showing heavy phytotoxic symptoms. The pH of the soil plays primordial role. The amounts ofCaCO3 which makes the medium alcaline, limits the bioavailability and the absorption of cadmium. Moreover, in hydroponic culture, the replacement of only 1/3 of nitric nitrogen by ammoniac leads to a physio logical acidification of the medium and triples the Cd content of the leaves. In soil, the use of(NH4)2.SO4 instead ofCa(NO3)2 produces similar results. The influence of the kind of nitrogen is certainly less important in the field than in pot culture but one can ask if the choice of nitrogen fertilizer isn't an easy and simple agriculture method of limiting Cd content in tobaccos.