Verimark^® and Exirel^® insect control are novel insecticides based on the active ingredient Cyazypyr^® (DPX-HGW86, cyantraniliprole) that belong to the second anthranilic diamide insecticides discovered by DuPont™. Verimark^® and Exirel^® are the first products in its class of chemistry that control a cross-spectrum of insect pests including Lepidoptera, Dipteran leafminers, fruit flies, beetles, whiteflies, thrips, aphids, leafhoppers, psyllids and weevils, while conserving key predators and parasitoids. Exirel^® and Verimark^® selectively activate the ryanodine receptor in insect muscles resulting in paralysis and rapid inhibition of feeding. Exirel^® has been optimized for foliar use, demonstrating excellent translaminar movement. Verimark^® has been optimized for soil applications to deliver consistent upward root systemicity. Data on the efficacy and residual control of foliar applications of Exirel^® and float house and at-plant transplant water applications of Verimark^® on flea beetles and tobacco budworm and their impact on crop establishment and potential crop yield benefits will be discussed. Both products have been granted reduced risk status on registered crops by the US Environmental Protection Agency (EPA), EPA approval for use on tobacco is anticipated for the 2016 growing season. (Reprinted with permission)